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Abnova™ Human LIFR (P42702, Gln 45 - Ser 833) Partial Recombinant Protein expressed in HEK293 cells
Description
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq]
Specifications
Specifications
| Accession Number | P42702 |
| For Use With (Application) | SDS-PAGE |
| Formulation | Lyophilized |
| Gene ID (Entrez) | 3977 |
| Molecular Weight (g/mol) | 125-135kDa |
| Name | LIFR (Human) Recombinant Protein |
| Preparation Method | Mammalian cell (HEK293) expression system |
| Purification Method | Ion exchange column and HPLC reverse phase column |
| Quantity | 20 μg |
| Storage Requirements | Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at 4°C for one month. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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