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Invitrogen™ Human LRRTM3 Synthetic Peptide

Artikelnummer. 15295209
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Quantity:
50 μg
Pakningsstørrelse:
50µg
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15295209 50 μg 50µg
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Artikelnummer. 15295209 Leverandør Invitrogen™ Leverandørnr. PEP1212

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Beskrivelse

Synthetic Peptide

LRRTM3 Synthetic Peptide, PEP-1212, from Invitrogen.

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the A-beta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma A-beta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
TRUSTED_SUSTAINABILITY

Tekniske data

Gene ID (Entrez) 347731
Species Human
Purification Method purified
Accession Number Q86VH5
Common Name Human LRRTM3
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol LRRTM3
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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