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Abnova™ Human MET (NM_000245.2, 956 a.a. - 1390 a.a.) Y1230A mutant Partial Protein expressed in Sf9 cells

Product Code. 16028036
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100 μg
Unit Size:
100µg
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Product Code. 16028036 Supplier Abnova™ Supplier No. P4827.100ug

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Description

Used for Func, SDS-PAGE

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Sequence: KKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMADKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS

Specifications

Accession Number NM_000245.2
Concentration 0.421 ug/uL
For Use With (Application) Functional Study, SDS-PAGE
Formulation Liquid
Gene ID (Entrez) 4233
Molecular Weight (g/mol) 78.695kDa
Name MET (Y1230A) (Human) Recombinant Protein
Preparation Method Insect cell (Sf9) expression system
Purification Method GST affinity chromatography
Quality Control Testing 2 ug/lane SDS-PAGE Stained with Coomassie Blue
Quantity 100 μg
Immunogen KKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMADKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing
Regulatory Status RUO
Gene Alias AUTS9/HGFR/RCCP2/c-Met
Common Name MET
Gene Symbol MET
Biological Activity 106pmol/μg x min
Species Baculovirus
Protein Tag None
Expression System Insect cell (Sf9) expression system
Form Liquid
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