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Invitrogen™ Human OBFC1 (aa 130-224) Control Fragment Recombinant Protein

Product Code. 30210430
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30210430

Brand: Invitrogen™ RP97057

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (72%), Rat (72%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111089 (PA5-111089. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

OBFC1 is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9H668
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79991
Name Human OBFC1 (aa 130-224) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 0610009H20Rik; 2310057J23Rik; AAF44; AAF-44; AI413458; alpha accessory factor 44; alpha-accessory factor of 44 kDa; bA541N10.2; CST complex subunit STN1; Obfc1; oligonucleotide/oligosaccharide binding fold containing 1; oligonucleotide/oligosaccharide-binding fold containing 1; oligonucleotide/oligosaccharide-binding fold-containing protein 1; replication protein A 32 kDa subunit; RPA-32; STN1; STN1 subunit of CST complex; STN1, CST complex subunit; suppressor of cdc thirteen homolog
Common Name OBFC1
Gene Symbol STN1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence DTIRVRGSIRTYREEREIHATTYYKVDDPVWNIQIARMLELPTIYRKVYDQPFHSSALEKEEALSNPGALDLPSLTSLLSEKAKEFLMENRVQSF
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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