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Abnova™ Human PAK6 kinase domain (Q9NQU5, 385 a.a. - 680 a.a.) Partial Recombinant Protein

Product Code. 16151850
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Quantity:
10 μg
Unit Size:
10µg
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16151850 10 μg 10µg
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Product Code. 16151850 Supplier Abnova™ Supplier No. P5386.10ug

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Description

Used for Func, SDS-PAGE

This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Specifications

Accession Number Q9NQU5
Concentration 1 mg/ml
For Use With (Application) Functional Study, SDS-PAGE
Formulation Liquid
Gene ID (Entrez) 56924
Molecular Weight (g/mol) 34.2kDa
Name PAK6 (Human) Recombinant Protein
Preparation Method Escherichia coli expression system
Quality Control Testing Loading 7 ug protein in SDS-PAGE
Quantity 10 μg
Immunogen GPHMVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTST The first 4 residues GPHM are from Turbo3C Protease cleavage site. The underlined S is phosphorylated S560.
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias PAK5
Common Name PAK6
Gene Symbol PAK6
Biological Activity Specific activity: 2,086pmoles/min/μg
Species E. coli
Recombinant Recombinant
Protein Tag None
Expression System Escherichia coli expression system
Form Liquid
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