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Gibco™ Human PDGF-AB Recombinant Protein, PeproTech®

Product Code. 17801763
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Product Code. Quantity unitSize
17801763 100 μg 100µg
17811763 10 μg 10µg
17860803 1 mg 1mg
17800483 250 μg 250µg
17820583 2 μg 2µg
17841153 500 μg 500µg
17860583 50 μg 50µg
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Product Code. 17801763 Supplier Gibco™ Supplier No. 10000AB100UG

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Description

Recombinant Protein

Recombinant Human PDGF-AB is a 26.4 kDa disulfide-linked dimer, consisting of one alpha chain and one beta chain (234 total amino acids). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P01127, P04085
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 5154, 5155
Molecular Weight (g/mol) 26.4 kDa
Name Human PDGF-AB
Quantity 100 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias Becaplermin; c-sis; H-PDGF-AB; IBGC5; PDGF A-chain; PDGF subunit A; PDGF subunit B; PDGF, B chain; PDGF1; PDGF-1; PDGF2; PDGF-2; Pdgfa; PDGF-A; PDGFAB; PDGFB; PDGF-B; platelet derived growth factor subunit A; platelet derived growth factor subunit B; platelet derived growth factor, alpha; platelet derived growth factor, B polypeptide; platelet-derived growth factor 2; platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor subunit A; Platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); proto-oncogene c-Sis; SIS; SSV
Common Name PDGF-AB
Gene Symbol PDGFA, PDGFB
Biological Activity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg
Conjugate Unconjugated
Recombinant Recombinant
Sequence Alpha chain: SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT Beta chain: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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