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Invitrogen™ Human RAB40B (aa 191-214) Control Fragment Recombinant Protein

Product Code. 30203126
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Quantity:
100 μL
Unit Size:
100µL
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30203126 100 μL 100µL
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Product Code. 30203126 Supplier Invitrogen™ Supplier No. RP109539

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140185 (PA5-140185. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q12829
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 10966
Name Human RAB40B (aa 191-214) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias GTP-binding protein homologous to Saccharomyces cerevisiae SEC4; protein Rar; RAB40B; Rab40b, member RAS oncogene family; rar; RAR SOCS box containing protein; ras-related protein Rab-40 B; sec4; SEC4L; SOCS box-containing protein RAR
Common Name RAB40B
Gene Symbol Rab40b
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SLQDLCCRAVVSCTPVHLVDKLPL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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