missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Gibco™ Human/Rat Neuritin Recombinant Protein, PeproTech®

Gibco™ Human/Rat Neuritin Recombinant Protein, PeproTech®

Product Code. 17854453
Click to view available options
Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
5µg
This item is not returnable. View return policy

Product Code. 17854453

Brand: Gibco™ 45036D250UG

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human/Rat Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Neuritin belongs to the neuritin family and is expressed in postmitotic-differentiating neurons of the developmental nervous system as well as neuronal structures associated with plasticity in adults. Its expression can be induced by neural activity and neurotrophins. The protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins and promotes neurite outgrowth and arborization, indicating its role in promoting neuritogenesis. Overexpression of the protein may be associated with astrocytoma progression. Alternative splicing leads to multiple transcript variants. NRN1 is associated with Severe Congenital Neutropenia 8 and Spinal Muscular Atrophy, Type III.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O08957, Q9NPD7
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 51299, 83834
Molecular Weight (g/mol) 19.4 kDa
Name Human/Rat Neuritin
Quantity 250 μg
Source E. coli
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 0710008J23Rik; Candidate plasticity gene 15 protein; candidate plasticity-related gene 15; Cpg15; dJ380B8.2; Neuritin; neuritin 1; NRN; NRN1
Common Name Neuritin
Gene Symbol NRN1
Biological Activity Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN
Content And Storage -20°C
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.