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STEMCELL Technologies Human Recombinant CNTF, ACF

Product Code. 17179741
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Product Code. 17179741

Brand: STEMCELL Technologies 78170

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This item is not returnable. View return policy

Description

Ciliary neurotrophic factor, animal component-free

  • Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that belongs to the four-helix bundle cytokine family and is structurally related to interleukin 6 (IL-6), interleukin 11 (IL-11), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
  • CNTF binds to its receptor CNFTRα and induces formation of a heterodimer of the signal transducing IL-6 receptor gp130 and LIF receptor (LIFR)-β, which triggers JAK/STAT, ERK, and PI3K signaling cascades
  • CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders
  • Additionally, CNTF is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes
  • This product is animal component-free

Specifications

Name Ciliary neurotrophic factor, HCNTF
Quantity 20 μg
Cell Type Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons
Purity or Quality Grade ≥95%
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