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STEMCELL Technologies Human Recombinant RANKL, ACF

Product Code. 17169861
Encompass_Preferred
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Product Code. 17169861

Brand: STEMCELL Technologies 78215.1

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This item is not returnable. View return policy

Receptor activator of nuclear factor kappa-B ligand, animal component-free

  • Receptor activator of nuclear factor kappa-B ligand (RANKL) is a member of the tumor necrosis factor (TNF) superfamily (Anderson et al.) Cytokines in the TNF superfamily are involved in a variety of long-term cellular activities such as differentiation, proliferation, and cell death (MacEwan)
  • RANKL is a type II homotrimeric transmembrane protein expressed in both a membrane-bound and secreted form (Ikeda et al.) RANKL binds to the receptor activator of nuclear factor kappa-B (RANK)
  • Upon binding to its receptor, RANKL activates the AKT signaling pathway (Moon et al.) Osteoprotegerin (OPG) may also bind RANKL, and this binding competes with RANKL-RANK binding (Lacey et al.) RANKL is involved in osteoclastogenesis (Lacey et al.; Yasuda et al.) and T cell activation (Wong et al.) This product is animal component-free

Specifications

Name CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoclast differentiation factor, soluble Receptor activator of NF-κB ligand, sOdf, TNF-related activation-induced cytokine, TNFSF11, TNF superfamily member 11, TNLG6B, Tumor necrosis factor superfamily member 11, TRAN
Quantity 100 μg
Cell Type Airway Cells; Cancer Cells and Cell Lines; Dendritic Cells; Intestinal Cells; Mammary Cells; Osteoblasts; Other; Pancreatic Cells; Prostate Cells; T Cells
Purity or Quality Grade ≥95%
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