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Invitrogen™ Human SGMS1 Control Fragment Recombinant Protein

Product Code. 30193940
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30193940

Brand: Invitrogen™ RP91301

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83764 (PA5-83764. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q86VZ5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 259230
Name Human SGMS1 Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 9530058O11Rik; AI841905; C80702; hmob33; Medulla oblongata-derived protein; MGC17342; MOB; MOB1; mob-1; Phosphatidylcholine:ceramide cholinephosphotransferase 1; protein Mob; SGMS1; SMS1; Sor1; sphingomyelin synthase 1; TMEM23; Transmembrane protein 23
Common Name SGMS1
Gene Symbol SGMS1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ASTMKEVVYWSPKKVADWLLENAMPEYCEPLEHFTGQDLINLTQEDFKKPPLCRVSSDNGQRLLDMIETLKMEHHLEAHKNGHANGHLNIGVDIPTPDGSFSIKIKPNGMPNGYRKEMIKIPM
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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