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Invitrogen™ Human SH3PXD2A (aa 902-986) Control Fragment Recombinant Protein

Product Code. 30213078
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30213078

Brand: Invitrogen™ RP97054

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58169 (PA5-58169. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q5TCZ1
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 9644
Name Human SH3PXD2A (aa 902-986) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2310014D11Rik; AA589508; Adapter protein TKS5; adaptor protein TKS5; AI256723; AI413738; C230050L11; EG329070; FISH; Five SH3 domain-containing protein; five SH3 domains; Gm5098; KIAA0418; SH3 and PX domain-containing protein 2 A; SH3 and PX domains 2 A; SH3 multiple domains 1; SH3 multiple domains protein 1; Sh3md1; SH3PXD2A; Tks5; TSK5; Tyrosine kinase substrate with five SH3 domains
Common Name SH3PXD2A
Gene Symbol Sh3pxd2a
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence PDPSGKELDTVPAKGRQNEGKSDSLEKIERRVQALNTVNQSKKATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSP
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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