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Invitrogen™ Human SOX17 ELISA Kit
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Quantity:
5 x 96 Tests
96 Tests
Unit Size:
Each
Pack of 96
Description
Human SOX17 quantitates human SOX17 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SOX17.
SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors. It acts as a transcription regulator that binds target promoter DNA and bends the DNA. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling. It promotes degradation of activated CTNNB1. SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm. Mutations in the gene can result in vesicoureteral reflux.
Specifications
Specifications
| Accession Number | HMG transcription factor SOX17; SOX17; Sox-17; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box 17; SRY-box containing gene 17; SRY-box transcription factor 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; VUR3 |
| Assay Range | 0.03 to 25 ng/mL |
| Assay Sensitivity | 0.03 ng/mL |
| Conjugate | HRP |
| Product Type | ELISA |
| Sample Type | Plasma, Serum, Supernatant |
| For Use With (Equipment) | Colorimetric Microplate Reader |
| Gene ID (Entrez) | 64321 |
| Gene Symbol | SOX17 |
| Interassay CV | <12% |
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