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Invitrogen™ Human SPANXC (aa 33-58) Control Fragment Recombinant Protein

Product Code. 30181653
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30181653

Brand: Invitrogen™ RP99048

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (42%), Rat (42%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83819 (PA5-83819. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NY87
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 64663
Name Human SPANXC (aa 33-58) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias C; cancer/testis antigen 11.3; cancer/testis antigen family 11, member 3; cancer/testis-associated protein CTp11; cancer/testis-associated protein of 11 kD; cancer-testis-associated protein CTp11; CT11.3; CTp11; nuclear-associated protein SPAN-Xc; SPANX family member C; SPANX family, member C; SPANXC; SPANX-C; SPAN-Xc protein; Sperm protein associated with the nucleus on the x chromosome C; sperm protein associated with the nucleus, x chromosome, family member C
Common Name SPANXC
Gene Symbol SPANXC
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SDPQPAPKKLKTSESSTILVVRYRRN
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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