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Gibco™ Human TMIGD2/CD28H Fc Recombinant Protein, PeproTech®

Product Code. 17822673
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Quantity:
1 mg
10 μg
100 μg
250 μg
50 μg
500 μg
Unit Size:
100µg
10µg
1mg
250µg
500µg
50µg
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Product Code. 17822673

Brand: Gibco™ 31042100UG

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Description

Recombinant Protein

CHO cell-derived Recombinant Human TMGID2/CD28H Fc is a glycosylated, disulfide-linked homodimer of 361-amino-acid-residues whose monomer consists of the 128-amino-acid extracellular domain fused to the 231-amino-acid length Fc portion of human IgG1 by two glycine residues. The calculated molecular weight of monomeric Recombinant TMIGD2/CD28H Fc is 40.1kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 55-60 kDa by SDS-PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins. TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q96BF3
For Use With (Application) ELISA, Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 126259
Molecular Weight (g/mol) 40.1 kDa
Name Human TMIGD2/CD28H Fc
Quantity 100 μg
Source CHO cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias CD28 homolog; CD28 homologue; CD28H; IGPR1; IGPR-1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor-1; TMIGD2; transmembrane and immunoglobulin domain containing 2; transmembrane and immunoglobulin domain-containing protein 2; transmembrane and immunoglobulin domain-containing protein 2 variant 2; transmembrane and immunoglobulin domain-containing protein 2 variant 3; UNQ3059/PRO9879
Common Name TMIGD2
Gene Symbol TMIGD2
Biological Activity Determined by its ability to bind recombinant human B7-H7 protein in a functional ELISA.
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence LSVQQGPNLL QVRQGSQATL VCQVDQATAW ERLRVKWTKD GAILCQPYIT NGSLSLGVCG PQGRLSWQAP SHLTLQLDPV SLNHSGAYVC WAAVEIPELE EAEGNITRLF VDPDDPTQNR NRIASFPGGG PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
Content And Storage -20°C
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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