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Gibco™ Human TPO (Thrombopoietin) Recombinant Protein, PeproTech®
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Quantity:
1 mg
10 μg
100 μg
2 μg
250 μg
50 μg
500 μg
Förpackningsstorlek
100µg
10µg
1mg
250µg
2µg
500µg
50µg
Beskrivelse
Recombinant Human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
Tekniske data
Tekniske data
| Accession Number | P40225 |
| For Use With (Application) | ELISA, Functional Assay, Western Blot |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 7066 |
| Molecular Weight (g/mol) | 18.6 kDa |
| Name | Human TPO (Thrombopoietin) |
| Quantity | 100 μg |
| Source | E. coli |
| Regulatory Status | RUO |
| Endotoxin Concentration | <1 EU/ μg |
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