missing translation for 'onlineSavingsMsg'
Learn More
Learn More
humanin Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
€ 145.00 - € 410.00
Specifications
| Antigen | humanin |
|---|---|
| Concentration | 0.23 mg/mL |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16804445
|
Proteintech
25886-1-AP-20UL |
20 μL |
€ 145.00
20µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
16894435
|
Proteintech
25886-1-AP-150UL |
150 μL |
€ 410.00
150µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Humanin is a novel 24 A. A polypeptide identified in Alzheimer′s disease-affected brain. It is 99% homologous to mitochondrial 16s ribosomal RNA and functions as a novel neuroprotective and cytoprotective factor. It specifically inhibits neuronal cell death induced by beta-amyloids and Alzheimer′s disease causing FAD genes by competitively inhibiting access of FPRL1 receptor to beta-amyloids. It acts as an anti-apoptotic factor by binding to Bcl-2/Bax family of pro-apoptotic factors including Bax, Bak, Bid and BimEL and inhibits their pro-apoptotic activity. It activates JAK/STAT signaling pathway and is regulated by TRIM11. It interacts with IGFBP-3 and specifically blocks IGFBP-3 induced cell death in glioblastoma cells. Humanin is also expressed in colon and testis.Specifications
| humanin | |
| Flow Cytometry, Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| Human | |
| Q8IVG9 | |
| 4550 | |
| Peptide | |
| Primary | |
| -20°C | |
| MT-RNR2 |
| 0.23 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| humanin, l rRNA, MTRNR2, RNR2 | |
| MT-RNR2 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title