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Proteintech HumanKine™ recombinant human IL-12 beta protein

Product Code. 17650087 Shop All Proteintech Products
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Quantity:
10 μg
100 μg
1000 μg
Unit Size:
1000µg
100µg
10µg
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Product Code. 17650087

Brand: Proteintech HZ13211000UG

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Description

HumanKine™ recombinant protein

IL-12p40, also known as IL-12B, is a subunit of both the IL-12 and IL-23 cytokines. It is not thought to be bioactive on its own, but it has been shown to regulate IL-12 activity in antagonistic manner by competitively binding with the IL-12 receptor. IL-12p40 also functions as a chemoattractant molecule for macrophage infiltration into tumor sites. There has additionally been evidence to suggest that IL-12p40 mediates a protective immune response against mycobacterial infection by serving as a necessary component for granuloma formation and promoting Th1 effector cell functions (PMID: 17126601, 10453037, 11739515).

Specifications

Accession Number P29460
Formulation 1 x PBS pH 7.4
Gene ID (Entrez) 3593
Molecular Weight (g/mol) 37-50 kDa
Quantity 1000 μg
Source HEK293
Storage Requirements Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.)
Endotoxin Concentration <0.1 EU/μg
Specific Reactivity Human
Recombinant Recombinant
Reconstitution Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 1 xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Form Lyophilized
Purity or Quality Grade >95%
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