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Invitrogen™ I-Ek Monoclonal Antibody (14-4-4S), Biotin
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Product Code. 15344041
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Quantity:
100 μg
Unit Size:
100µg
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15344041 100 μg 100µg
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Product Code. 15344041 Supplier Invitrogen™ Supplier No. MA517761

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Description

Mouse Monoclonal Antibody

MA5-17761 targets I-Ek in FACS applications and shows reactivity with Mouse samples. The MA5-17761 immunogen is c3H.

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
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Specifications

Antigen I-Ek
Applications Flow Cytometry
Classification Monoclonal
Clone 14-4-4S
Concentration 0.1 mg/mL
Conjugate Biotin
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene H2-Eb1
Gene Accession No. P04230, P14439
Gene Alias AI323765; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia3; Ia-3; Ia4; Ia-4; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; major histocompatibility complex H-2E beta chain; MGC117888; MHC class II antigen E alpha; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein
Gene Symbols H2-Ea-ps, H2-Eb1
Host Species Mouse
Immunogen C3H.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100504404, 14969
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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