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Icilin, MedChemExpress

Product Code. p-200099937
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
16440707 50 mg 50mg
16424388 10 mg 10mg
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Product Code. 16440707

Brand: Medchem Express HY11062

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Description

MedChemExpress Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a 'super-cooling agent'. Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response.

Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a 'super-cooling agent'. Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response.

Specifications

Chemical Name or Material Icilin
CAS 36945-98-9
Color Yellow
Purity Grade Notes Research
Molecular Formula C16H13N3O4
Quantity 50 mg
Synonym AG-3-5
Solubility Information DMSO : ≥ 54 mg/mL (173.47 mM)
SMILES O=C1N(C2=CC=CC=C2O)CC=C(C3=CC=CC([N+]([O-])=O)=C3)N1
Molecular Weight (g/mol) 311.29
Formula Weight 311.29
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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