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Invitrogen™ ICK Polyclonal Antibody

Description
Immunogen sequence: DFSPSLSRID LKNKKRQSDD TLCRFESVLD LKPSEPVGTG NSAPTQTSYQ RRDTPTLRSA AKQHYLKHSR YLPGISIRNG ILSNPGKEFI PPNPWSSSGL SGKSSGTMSV ISKVNSVGSS Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 80%.
ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems.
Specifications
Specifications
| Antigen | ICK |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CILK1 |
| Gene Accession No. | Q9UPZ9 |
| Gene Alias | 2210420N10Rik; AI848300; ciliogenesis associated kinase 1; CILK1; ECO; heart serine-threonine protein kinase; hICK; iciliogenesis associated kinase 1; ICK; intestinal cell (MAK-like) kinase; intestinal cell kinase; KIAA0936; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; mICK; MRK; serine/threonine protein kinase; serine/threonine-protein kinase ICK |
| Gene Symbols | CILK1 |
| Show More |
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