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Invitrogen™ IDH3A Polyclonal Antibody
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Product Code. 13454607
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Quantity:
100 μL
Unit Size:
100µL
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13454607 100 μL 100µL
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Product Code. 13454607 Supplier Invitrogen™ Supplier No. PA530069

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Raji, mouse brain, rat brain. Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (88%), Xenopus laevis (88%), Chicken (92%), Rhesus Monkey (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IDH3A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.63 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene IDH3A
Gene Accession No. P50213, Q99NA5, Q9D6R2
Gene Alias 1110003P10Rik; 1500012E04Rik; AA407078; AI316514; H-IDH alpha; Idh3a; isocitrate dehydrogenase (NAD(+)) 3 alpha; isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; isocitrate dehydrogenase 3 (NAD(+)) alpha; isocitrate dehydrogenase 3 (NAD+) alpha; isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; NAD+-specific ICDH
Gene Symbols IDH3A
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human IDH3A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114096, 3419, 67834
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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