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Invitrogen™ Iduronate 2 Sulfatase Polyclonal Antibody
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Product Code. 15547482
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Quantity:
100 μg
Unit Size:
100µg
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15547482 100 μg 100µg
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Product Code. 15547482 Supplier Invitrogen™ Supplier No. PA546990

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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IDS is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Iduronate 2 Sulfatase
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Ids
Gene Accession No. P22304
Gene Alias alpha-L-iduronate sulfate sulfatase; AW214631; Ids; Iduronate 2-sulfatase; iduronate 2-sulfatase (Hunter syndrome); iduronate 2-sulfatase 14 kDa chain; Iduronate 2-sulfatase 42 kDa chain; iduronate sulfatase; iduronate-2-sulfatase; idursulfase; MPS2; SIDS
Gene Symbols Ids
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human IDS Ser26-Pro550.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3423
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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