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Invitrogen™ IFI6 Polyclonal Antibody
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Product Code. 16604075
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Quantity:
100 μL
Unit Size:
100µL
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16604075 100 μL 100µL
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Product Code. 16604075 Supplier Invitrogen™ Supplier No. PA599824

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IFI6.

G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins. Localized to the mitochondria, G1P3 is a multi-pass membrane protein that is induced by IFN-α2β. G1P3 has been shown to play a major role in the apoptosis pathway. Specifically, G1P3 acts as a cell survival protein by inhibiting caspase-3 activity, which antagonizes apoptosis. G1P3 has been implicated in tumorigenesis and is the subject of therapeutic studies, as reducing G1P3-mediated antiapoptotic signals could suggest improved therapies for myeloma or other malignancies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFI6
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IFI6
Gene Accession No. P09912
Gene Alias 6-16; FAM14C; G1P3; IFI6; IFI616; IFI-6-16; interferon alpha inducible protein 6; interferon alpha-inducible protein 6; interferon, alpha-inducible protein 6; interferon, alpha-inducible protein clone IFI-6-16; interferon-induced protein 6-16
Gene Symbols IFI6
Host Species Rabbit
Immunogen A synthesized peptide derived from human IFI6(Accession P09912), corresponding to amino acid residues A5-G55.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2537
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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