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Invitrogen™ IFN omega Monoclonal Antibody (OMG-5), eBioscience™
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Product Code. 15571317
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Quantity:
100 μg
Unit Size:
100µg
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15571317 100 μg 100µg
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Product Code. 15571317 Supplier Invitrogen™ Supplier No. BMS1021

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Description

Mouse Monoclonal Antibody

Description: Anti-human IFN-omega (OMG-5) neutralize the antiviral activity of IFN-omega. In the human genome, the IFN-omega gene family consists of seven members located on chromosome 9. However, only one of these genes is functional giving rise to the IFN-omega protein, whereas the others are non-functional pseudogenes. The IFN-omega gene is not expressed in unstimulated cells. Viral infection results in expression of the gene giving rise to the N-glycosylated protein consisting of 172 or 174 amino acids and an apparent molecular mass of about 25kDa. A single carbohydrate group consists mainly of biantennary complex oligosaccharides with variable amounts of N-acetyl neuraminic acid. In quantitative terms, IFN-omega is a major component of human leukocyte IFN; with a contribution to its total antiviral activity estimated to be in the range of 10 -15 %. Applications Tested: ELISA.

IFN-omega is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds that are necessary for full biological activity.
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Specifications

Antigen IFN omega
Applications ELISA
Classification Monoclonal
Clone OMG-5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2-7.4
Gene IFNW1
Gene Accession No. P05000
Gene Alias IFN o; IFN ω; IFNo; IFNomega; IFN-omega 1, interferon omega-1; IFNW; IFNW1; IFNω; Interferon; Interferon alpha-II-1; Interferon o; Interferon OMEGA; interferon omega 1; interferon omega-1; Interferon ω; interferon, omega 1
Gene Symbols IFNW1
Host Species Mouse
Immunogen Rec. Human IFN omega.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3467
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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