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  6. 17779003

Invitrogen™ IFNAR1 Monoclonal Antibody (A5-A3)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA542390

Product Code. 17779003

  • € 504.00 / 100µL

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This item is not returnable. View return policy

Description

Description

Positive Control: K562, A431, Siha, mouse brain tissue lysate, NCCIT, SHUG-44, human lung tissue, human skin tissue, human colon tissue. Subcellular Location: Endosome. Cell membrane.

Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

IFNAR1
Monoclonal
2 mg/mL
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
P17181, P33896
Ifnar1
Recombinant protein within human IFNAR1 aa 28-127 (Extracellular).
100 μL
Primary
Human, Mouse
Antibody
IgG1
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
A5-A3
Unconjugated
Ifnar1
alpha-type antiviral protein; AVP; beta-type antiviral protein; CD118; CRF2-1; cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; H3K1; Ifar; IFN R1; IFNalpha/beta R1; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFNalpha/betaR1; IFN-alpha/betaR1; IFN-alpha/betaRalpha; IFNalpha/beta-Ralpha; IFN-alpha-REC; IFNAR; Ifnar1; IFNBR; IFNR1; IFN-R-1; Ifrc; INF-a receptor; Infar; interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha and beta receptor subunit 1; interferon alpha/beta receptor 1; interferon receptor 1; interferon-alpha/beta receptor 1; interferon-alpha/beta receptor alpha chain; interferon-beta receptor 1; type I interferon receptor 1
Mouse
Protein G
RUO
15975, 3454
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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