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Invitrogen™ IFNAR2 Recombinant Rabbit Monoclonal Antibody (122), FITC
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Product Code. 17451113
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100 Tests
Unit Size:
100 tests
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17451113 100 Tests 100 tests
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Product Code. 17451113 Supplier Invitrogen™ Supplier No. MA540953

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Description

Rabbit Recombinant Monoclonal Antibody

May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.

The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IFNAR2
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 122
Concentration 0.1 mg/mL
Conjugate FITC
Formulation PBS with 0.5% BSA and 0.03% ProClin 300
Gene IFNAR2
Gene Accession No. P48551
Gene Alias AI747302; human interferon alpha/beta receptor; IFN alpha/betaRbeta; IFN R2; IFNABR; IFNalpha/beta R2; IFN-alpha/beta receptor 2; IFNalpha/betaR2; IFN-alpha/betaR2; IFN-alpha/betaRbeta; IFNalpha/beta-Rbeta; IFN-alpha-REC; IFNAR2; Ifnar-2; IFNARB; IFN-R; IFNR2; IFN-R-2; IMD45; interferon (alpha and beta) receptor 2; interferon (alpha, beta and omega) receptor 2; interferon alpha and beta receptor subunit 2; interferon alpha binding protein; Interferon alpha/beta receptor 2; interferon receptor 2c; interferon-alpha/beta receptor 2; interferon-alpha/beta receptor beta chain; type I interferon alpha/beta receptor 2a; type I interferon receptor 2
Gene Symbols IFNAR2
Host Species Rabbit
Immunogen Recombinant Human IFNAR2 Protein.
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3455
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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