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IFT57 Monoclonal Antibody (OTI5B6), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA500906
This item is not returnable.
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Description
HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.Specifications
| IFT57 | |
| Monoclonal | |
| 0.53 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9NWB7 | |
| IFT57 | |
| Full length human recombit protein of human IFT57 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI5B6 | |
| Unconjugated | |
| IFT57 | |
| ESRRBL1, HIPPI, MHS4R2 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 55081 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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