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  6. IGF1R beta chain Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

IGF1R beta chain Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16899774 Shop All Proteintech Products
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150 μL
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20µL
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16899774 20 μL 20µL
16889774 150 μL 150µL
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Product Code. 16899774 Supplier Proteintech Supplier No. 202541AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody raised against a synthesized polypeptide (CGVLVLRASFDERQPYAH) corresponding to 1332-1348aa of human IGF1R protein recognizes beta subunit of IGF1R.

IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of maligt cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.

Specifications

Antigen IGF1R beta chain
Applications Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene IGF1R
Gene Accession No. P08069, P24062, Q60751
Gene Alias CD221, IGF I receptor, IGF1R, IGFIR, IGFR, JTK13
Gene Symbols IGF1R
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16001, 25718, 3480
Target Species Mouse, Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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