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Invitrogen™ IGF2BP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA5120252

Product Code. 17721654

€ 504.00 / 100µL

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Description

Positive test controls include: HeLa, Jurkat, Mouse testis, Mouse ovary, Rat testis. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: NFFNPKEEVK LEAHIRVPSS TAGRVIGKGG KTVNELQNLT SAEVIVPRDQ TPDENEEVIV RIIGHFFASQ TAQRKIREIV QQVKQQEQKY PQGVASQRSK.

IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.

Specifications

Antigen	IGF2BP2
Classification	Polyclonal
Conjugate	Unconjugated
Gene	IGF2BP2
Gene Alias	C330012H03Rik; Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF2BP2; IGF-II mRNA-binding protein 2; Imp2; IMP-2; insulin like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA binding protein 2; insulin-like growth factor 2 mRNA-binding protein 2; insulin-like growth factor 2, binding protein 2; Neilsen; p62; RGD1305614; VICKZ family member 2; VICKZ2
Host Species	Rabbit
Purification Method	Affinity Chromatography
Regulatory Status	RUO
Gene ID (Entrez)	10644, 303824, 319765
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Concentration	1.58 mg/mL
Formulation	PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.	Q5SF07, Q9Y6M1
Gene Symbols	IGF2BP2
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 500-599 of human IGF2BP2/IMP2 (NP_0065393).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse, Rat
Product Type	Antibody
Isotype	IgG

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Invitrogen™ IGF2BP2 Polyclonal Antibody

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