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Invitrogen™ IGF2BP3 Polyclonal Antibody

Product Code. 15685055
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Quantity:
100 μL
Unit Size:
100µL
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15685055 100 μL 100µL
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Product Code. 15685055 Supplier Invitrogen™ Supplier No. PA551136

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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total IGF2BP3 protein.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IGF2BP3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene IGF2BP3
Gene Accession No. O00425
Gene Alias 2610101N11Rik; AA522010; Ab2-255; AL022933; AU045931; cancer/testis antigen 98; CT98; hKOC; IGF2 mRNA-binding protein 3; IGF2BP3; IGF-II mRNA-binding protein 3; IMP3; IMP-3; insulin like growth factor 2 mRNA binding protein 3; insulin-l; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2, binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC; KOC1; Koc13; mimp3; mIMP-3; Neilsen; RGD1306512; VICKZ family member 3; Vickz3
Gene Symbols IGF2BP3
Host Species Rabbit
Immunogen Fusion protein of human IGF2BP3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10643
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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