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PeproTech IGFBP-1 Polyclonal Antibody, PeproTech®, Invitrogen™
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Product Code. p-7245308
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50µg
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Product Code. Quantity unitSize
17835163 50 μg 50µg
17825793 100 μg 100µg
17805783 1 mg 1mg
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Product Code. 17835163 Supplier PeproTech Supplier No. 500P22850UG

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Description

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN. Preparation: Produced from sera of rabbits immunized with highly pure recombinant Human IGF-BP1. Anti-Human IGF-BP1-specific antibody was purified by affinity chromatography employing an immobilized Human IGF-BP1 matrix. Sandwich ELISA: To detect Human IGF-BP1 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human IGF-BP1 (500-P228Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human IGF-BP1. Western Blot: To detect Human IGF-BP1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human IGF-BP1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
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Specifications

Antigen IGFBP-1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene IGFBP1
Gene Accession No. P08833
Gene Alias AFBP; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; hIGFBP-1; IBP 1; IBP1; IBP-1; IGF BP25; IGFBA; IGF-binding protein 1; IGFBP; IGFBP 1; Igfbp1; Igfbp-1; IGF-BP25; Insulin like growth factor binding protein; insulin like growth factor binding protein 1; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12
Gene Symbols IGFBP1
Host Species Rabbit
Immunogen E.coli-derived Recombinant Human IGF-BP1.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3484
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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