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Invitrogen™ IkB zeta Recombinant Rat Monoclonal Antibody (LK2NAP)

Rat Recombinant Monoclonal Antibody

€ 218.00 - € 442.00

Specifications

Antigen IkB zeta
Clone LK2NAP
Concentration 1.0 mg/mL
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications Flow Cytometry, Western Blot, Immunocytochemistry
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30276570
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Invitrogen™
740065T
100 μL
€ 442.00
100µg
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30276626
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Invitrogen™
740065T20UG
20 μL
€ 218.00
20µg
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Description

Description

Recombinant rat monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

I-kappa-B-zeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.
Specifications

Specifications

IkB zeta
1.0 mg/mL
Flow Cytometry, Western Blot, Immunocytochemistry
Unconjugated
Rat
RUO
PBS with 0.09% sodium azide; pH 7.4
Q9BYH8, Q9EST8
304005, 64332, 80859
Primary
Affinity chromatography
LK2NAP
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Recombinant Monoclonal
Liquid
IgG2a
Human, Mouse, Rat
NFKBIZ
AA408868; FLJ30225; FLJ34463; Ikappa B-zeta variant 3; ikappaBzeta; I-kappa-B-zeta; IkappaB-zeta; IKBZ; ikB-zeta; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; molecule possessing ankyrin repeats induced by lipopolysaccharide; molecule possessing ankyrin-repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKB inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; OTTHUMP00000214340; RGD1310834
NFKBIZ
Antibody
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