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IKZF3 Monoclonal Antibody (OTI2B9), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA804393
This item is not returnable.
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Description
IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.Specifications
| IKZF3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q9UKT9 | |
| IKZF3 | |
| Human recombit protein fragment corresponding to amino acids 1-301 of human IKZF3 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI2B9 | |
| Unconjugated | |
| IKZF3 | |
| AIO, AIOLOS, ZNFN1A3 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 22806 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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