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IKZF3 Mouse anti-Human, Clone: OTI7E11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Brand:  Origene Technologies CF804396

Encompass_Preferred

Product Code. 17657971

  • € 726.00 / 100µg

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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Specifications

Specifications

IKZF3
Monoclonal
Unconjugated
IKZF3
AIO, AIOLOS, ZNFN1A3
Mouse
Affinity Chromatography
RUO
22806
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI7E11
PBS with 8% trehalose and no preservative; pH 7.3
Q9UKT9
IKZF3
Human recombit protein fragment corresponding to amino acids 1-301 of human IKZF3 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG2b
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