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Invitrogen™ IKZF3 Recombinant Rabbit Monoclonal Antibody (4U7F9)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA542889
This item is not returnable.
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Description
Positive test controls include: Raji, Mouse spleen, Mouse thymus, Rat lung. Immunogen sequence: IYQQNHMVLS RARNGMPLLK EVPRSYELLK PPPICPRDSV KVINKEGEVM DVYRCDHCRV LFLDYVMFTI HMGCHGFRDP FECNMCGYRS HDRYEFSSHI ARGEHRALLK.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Specifications
| IKZF3 | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O08900, Q9UKT9 | |
| Ikzf3 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 400-509 of human IKZF3 (Q9UKT9). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 4U7F9 | |
| Unconjugated | |
| Ikzf3 | |
| 5830411O07Rik; AIO; AIOLOS; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); ikaros family zinc finger protein 3; Ikzf3; Zfpn1a3; zinc finger DNA binding protein Aiolos; zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); Znfn1a3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 22780, 22806, 303511 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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