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Invitrogen™ IL-10 Recombinant Rabbit Monoclonal Antibody (128), Biotin
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Product Code. 30019298
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Quantity:
100 μg
Unit Size:
100µg
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30019298 100 μg 100µg
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Product Code. 30019298 Supplier Invitrogen™ Supplier No. MA552267

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Description

Rabbit Recombinant Monoclonal Antibody

IL-10 Recombinant Monoclonal Antibody for ELISA

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
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Specifications

Antigen IL-10
Applications ELISA
Classification Recombinant Monoclonal
Clone 128
Concentration 100 μg/mL
Conjugate Biotin
Formulation PBS with no preservative
Gene IL10
Gene Accession No. P22301
Gene Alias CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
Gene Symbols IL10
Host Species Rabbit
Immunogen Recombinant Human IL10/IL-10/Interleukin-10 Protein (Ser19-Asn178).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3586
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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