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IL-2 Rat anti-Mouse, APC, Clone: JES6-5H4, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 562041
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Description
The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2R β (CD122) and common gamma chain ( γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2R α (CD25), IL-2R β and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.
Specifications
| IL-2 | |
| Monoclonal | |
| 0.2mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse IL-2 Recombinant Protein | |
| 25 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| JES6-5H4 | |
| APC | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2b |
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