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IL-4 Rat anti-Mouse, Functional Grade, Clone: 11B11, eBioscience™
Rat Monoclonal Antibody
Merk: Affymetrix eBioscience 16-7041-85
Overige gegevens : Gewicht : 0.01000kg
Beschrijving
A standard curve consisting of doubling dilutions of the recombit standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.Specificatie
IL-4 | |
Monoclonal | |
1 mg/mL | |
PBS with no preservative; pH 7.2 | |
P07750 | |
Interleukin-4, BSF1, IL-4, Lymphocyte stimulatory factor 1, MGC79402 | |
Rat | |
Affinity chromatography | |
RUO | |
Antibody | |
Monoclonal | |
Mouse |
ELISA, Functional Assay | |
11B11 | |
Functional Grade | |
Il4 | |
Liquid | |
Il4 | |
IgG1, kappa | |
500 μg | |
4° C | |
Primary | |
16189 |
For Research Use Only.