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IL-4 Rat anti-Mouse, Functional Grade, Clone: 11B11, eBioscience™

Rat Monoclonal Antibody

Merk:  Affymetrix eBioscience 16-7041-85

Overige gegevens : Gewicht : 0.01000kg

 Bekijk meerdere types van dit product via de

Produktcode. 15248747

  • € 274.00 / 500 µg


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Beschrijving

Beschrijving

A standard curve consisting of doubling dilutions of the recombit standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Specificatie

Specificatie

IL-4
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P07750
Interleukin-4, BSF1, IL-4, Lymphocyte stimulatory factor 1, MGC79402
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
ELISA, Functional Assay
11B11
Functional Grade
Il4
Liquid
Il4
IgG1, kappa
500 μg
4° C
Primary
16189
Video's
Documentatie

For Research Use Only.