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Invitrogen™ IL10RA Monoclonal Antibody (OTI1D10)

Description
IL10RA Monoclonal Antibody for Western Blot, IHC (P)
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Specifications
Specifications
| Antigen | IL10RA |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI1D10 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | Il10ra |
| Gene Accession No. | Q13651 |
| Gene Alias | AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R |
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