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Invitrogen™ IL10RA Polyclonal Antibody
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Product Code. 15518152
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Quantity:
100 μg
Unit Size:
100µg
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15518152 100 μg 100µg
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Product Code. 15518152 Supplier Invitrogen™ Supplier No. PA547657

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Description

Goat Polyclonal Antibody

In direct ELISAs and Western blots, less than 25% cross-reactivity with recombinant human IL-10 R alpha is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL10RA
Applications Neutralization, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Il10ra
Gene Accession No. Q61727
Gene Alias AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R
Gene Symbols Il10ra
Host Species Goat
Immunogen Sf 21-derived recombinant mouse IL-10 R alpha Thr24-Asn238 (Lys188Arg and Glu222Gly).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16154
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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