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IL12B Mouse anti-Human, Clone: OTI1A3, liquid, TrueMAB™

Product Code. 17547923
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100 μL
Unit Size:
100µL
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17547923 100 μL 100µL
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Product Code. 17547923 Supplier Origene Technologies Supplier No. TA807426

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Mouse Monoclonal Antibody

IL12B (IL-12 p40) encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.

Specifications

Antigen IL12B
Applications Western Blot
Classification Monoclonal
Clone OTI1A3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene IL12B
Gene Accession No. P29460
Gene Alias CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
Gene Symbols IL12B
Host Species Mouse
Immunogen Full length human recombit protein of human IL12B produced in SF9 cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3593
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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