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IL12RB1 Mouse anti-Human, Clone: OTI1A6, lyophilized, TrueMAB™

Product Code. 17659701
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100 μg
Unit Size:
100µg
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17659701 100 μg 100µg
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Product Code. 17659701 Supplier Origene Technologies Supplier No. CF808195

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Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Specifications

Antigen IL12RB1
Applications Western Blot
Classification Monoclonal
Clone OTI1A6
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene IL12RB1
Gene Accession No. P42701
Gene Alias CD212, IL-12R-BETA1, IL12RB, IMD30
Gene Symbols IL12RB1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 33-283 of human IL12RB1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3594
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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