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Invitrogen™ IL17RA Monoclonal Antibody (133621)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561041
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
Specifications
| IL17RA | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q96F46 | |
| Il17ra | |
| Mouse myeloma cell line NS0-derived recombinant human IL-17 RA/IL-17 R, Leu33-Trp320. | |
| 500 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| ELISA, Western Blot | |
| 133621 | |
| Unconjugated | |
| Il17ra | |
| AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 23765 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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