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Invitrogen™ IL17RC Polyclonal Antibody
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Product Code. 15762041 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15762041 100 μL 100µL
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Product Code. 15762041 Supplier Invitrogen™ Supplier No. PA554108

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WDSDILCLPG DIVPAPGPVL APTHLQTELV LRCQKETDCD LCLRVAVHLA VHGHWEEPED EEKFGGAADS GVEEPRNASL QAQVVLSFQA YPTARCVLLE VQVPAALVQF GQSVGSVVYD CFEAALGSEV RIWSYTQPRY EKELNH Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 76%.

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IL17RC
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IL17RC
Gene Accession No. Q8NAC3
Gene Alias 1110025H02Rik; CANDF9; Gm19850; IL-17 receptor C; IL17F receptor; IL17RC; IL-17RC; IL17-RC; IL17Rhom; Il17rl; IL-17RL; IL17-RL; interleukin 17 receptor C; interleukin-17 receptor C; Interleukin-17 receptor homolog; interleukin-17 receptor-like protein; UNQ6118/PRO20040/PRO38901; ZcytoR14
Gene Symbols IL17RC
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IL17RC. Recombinant protein control fragment (Product #RP-90444).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84818
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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