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Invitrogen™ IL17RE Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA589747
This item is not returnable.
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Description
Immunogen sequence: AGIGFRHLPH WNTRCPLASH TDDSFTGSSA YIPCRTWWAL FSTKPWCVRV WHCSRCLCQH LLSGGSGLQR GLFHLLVQKS KKSSTFKFYR RHKMPAPAQR KLLPRRHLSE KSHHISIPSP DISHKGLRSK RTQPSDPETW ESLPRLDSQR HGGPEFSFDL LPEARAIRVT ISSGPEVSVR LCHQWALECE ELSSPYDVQK IVSGGHTVEL PYEFLLPCLC IEASYLQEDT VRRKKCP; Positive Samples: HT-29, A-549, A-431, Mouse kidney, Mouse thymus; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein.
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
Specifications
| IL17RE | |
| Polyclonal | |
| Unconjugated | |
| IL17RE | |
| AA589509; IL-17 receptor E; IL17RE; IL-17RE; Il25r; interleukin 17 receptor E; interleukin-17 receptor E; UNQ3056/PRO9877 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 132014, 57890 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.98 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| Q8BH06, Q8NFR9 | |
| IL17RE | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 24-260 of human IL17RE (NP_7056131). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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