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IL24 Mouse anti-Human, Clone: OTI3C5, liquid, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies TA809390
This item is not returnable.
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Description
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in maligt gliomas in a p53-independent manner.Specifications
| IL24 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q13007 | |
| IL24 | |
| Human recombit protein fragment corresponding to amino acids 52-206 of human IL24 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI3C5 | |
| Unconjugated | |
| IL24 | |
| C49A, FISP, IL10B, MDA7, MOB5, ST16 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 11009 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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