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Invitrogen™ IGF2BP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530398

Product Code. 13414897

  • € 520.00 / 100µL

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Description

Description

Recommended positive controls: PC-3, SK-N-SH. Predicted reactivity: Mouse (98%), Zebrafish (80%), Xenopus laevis (83%), Chicken (82%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

IGF2BP3
Polyclonal
Unconjugated
IGF2BP3
2610101N11Rik; AA522010; Ab2-255; AL022933; AU045931; cancer/testis antigen 98; CT98; hKOC; IGF2 mRNA-binding protein 3; IGF2BP3; IGF-II mRNA-binding protein 3; IMP3; IMP-3; insulin like growth factor 2 mRNA binding protein 3; insulin-l; insulin-like growth factor 2 mRNA binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2, binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC; KOC1; Koc13; mimp3; mIMP-3; Neilsen; RGD1306512; VICKZ family member 3; Vickz3
Rabbit
Antigen affinity chromatography
RUO
10643
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.56 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
O00425
IGF2BP3
Recombinant protein encompassing a sequence within the center region of human IMP3. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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