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Invitrogen™ Importin 7 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521764

Product Code. 13239988

  • € 566.00 / 100µg

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This item is not returnable. View return policy

Description

Description

Recommended positive controls: A549, HeLa, Jurkat, NT2D1. Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of RaNULLs GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Importin 7
Polyclonal
Unconjugated
Ipo7
A330055O14Rik; C330016G14; FLJ14581; Imp7; importin 7; importin-7; IPO7; MGC138673; RAN binding protein 7; RAN-binding protein 7; RanBP7
Rabbit
Antigen affinity chromatography
RUO
10527
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 10% glycerol and 0.01% thimerosal; pH 7
O95373
Ipo7
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Importin 7. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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