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DiscoverX InCELL Hunter™ eXpress HEK 293 BRDT(1,2) Bromodomain Assay

Product Code. 17374789
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17374789

Brand: DiscoverX 960046E1CP7M

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This item is not returnable. View return policy

Description

The InCELL Hunter™ eXpress HEK 293 BRDT(1,2) Bromodomain Assay measures target engagement via compound-induced stabilization of BRDT(1,2) target protein. eXpress kits contain all assay materials: cells, reagents, and plates.

The InCELL Hunter™ eXpress HEK 293 BRDT(1,2) Bromodomain Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with regulators of epigenetics pathways. This kit assesses compound-engagement-based stabilization of BRDT(1,2) via detection of BRDT(1,2) levels. This product uses EFC technology. The cell line included overexpresses BRDT(1,2) target protein fused to PL. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry HEK 293
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist (+)-JQ1
Quantity 200 dp (2 x 96-well)
Target Entry BRDT(1,2)
Cell Line 293H
Target BRDT(1,2)
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